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AFE DIC Fibrinogen Replacement — FRCA Final MCQ

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HardObstetric AnaesthesiaAFE DIC Fibrinogen ReplacementFRCA Final

Post-CS: acutely breathless, cyanosed, BP 60/30, DIC on bloods. Fibrinogen 0.8 g/L. What dose of fibrinogen concentrate?

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Correct answer: C4 g IV guided by ROTEM

Suspected AFE with DIC: fibrinogen concentrate 4g IV guided by FIBTEM A5 on ROTEM is appropriate for severe hypofibrinogenaemia. FFP alone insufficient (only ~2 g/L fibrinogen). Target fibrinogen >2 g/L in obstetric haemorrhage.

Reference: OAA – 2023 – AFE management; BSH – 2022 – Major obstetric haemorrhage