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Sickle Cell Perioperative Management — FRCA Final MCQ

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ModerateGeneral AnaesthesiaSickle Cell Perioperative ManagementFRCA Final

A 28-year-old woman with HbSS disease requires emergency appendicectomy under GA. Most important intraoperative strategy to prevent sickling?

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Correct answer: CMaintain core temp >36°C, avoid hypoxia and dehydration

Preventing sickling: avoid hypothermia, hypoxia, dehydration, acidosis, venous stasis. Maintain normothermia >36°C, SpO2 >95%, euvolaemia. Exchange transfusion to HbS <30% reserved for high-risk surgery (cardiac, intracranial). Regional anaesthesia is not contraindicated.

Reference: BSH – 2022 – Management of sickle cell disease in surgical settings