Parkinsons Disease Drug Avoidance — FRCA Final MCQ

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ModerateGeneral AnaesthesiaParkinsons Disease Drug AvoidanceFRCA Final

A 72-year-old man with Parkinson's disease is listed for elective hip replacement. Which anaesthetic-related drug is most important to avoid?

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Correct answer: C — Droperidol

Droperidol and metoclopramide are D2 antagonists that dramatically worsen Parkinsonian symptoms and risk NMS-like syndrome. Domperidone is safe (doesn't cross BBB). Ondansetron and cyclizine are safe alternatives. PD medications must be continued perioperatively.

Reference: RCOA/BGS – 2023 – Perioperative care of people with Parkinson's disease