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GLP-1 RA Preoperative Management — FRCA Final MCQ

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ModerateGeneral AnaesthesiaGLP-1 RA Preoperative ManagementFRCA Final

A 42-year-old woman on weekly oral semaglutide 14 mg is scheduled for laparoscopic Nissen fundoplication. How should this be managed preoperatively?

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Correct answer: BHold for 7 days before surgery

GLP-1 RAs (semaglutide, liraglutide) delay gastric emptying, increasing aspiration risk. ASA 2023 consensus: hold weekly GLP-1 RAs for ≥7 days before elective surgery. If not held for full period, perform POCUS gastric ultrasound and treat as full stomach if significant residual volume.

Reference: ASA – 2023 – Consensus guidance on preoperative management of GLP-1 receptor agonists