Oxygen Dissociation Curve Right Shift — FRCA Final MCQ
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Correct answer: C — Increased 2,3-DPG, acidosis, pyrexia, and hypercarbia
Right shift of the ODC (decreased oxygen-haemoglobin affinity, increased P50, easier O2 release to tissues) is caused by: increased 2,3-DPG, acidosis (Bohr effect), pyrexia, and hypercarbia. Left shift (increased affinity, harder O2 release): alkalosis, hypothermia, fetal Hb, carboxyhaemoglobin, methaemoglobin, decreased 2,3-DPG.
Reference: RCOA – 2023 – Respiratory physiology: oxygen transport