Obstructive Jaundice Post-Cholecystectomy — FRCA Final MCQ
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Correct answer: A — Post-hepatic (obstructive/cholestatic)
Common bile duct clipping/injury causes post-hepatic (obstructive) jaundice. Bile cannot drain into the duodenum, causing: conjugated (direct) hyperbilirubinaemia, elevated ALP and GGT (cholestatic enzymes), dark urine (conjugated bilirubin is water-soluble and excreted renally), pale stools (absent urobilinogen/stercobilin), and pruritus (bile salt deposition in skin). ALT may be mildly elevated from back-pressure damage to hepatocytes. Diagnosis: ultrasound showing dilated bile ducts, confirmed by MRCP. Management: ERCP with stenting or surgical repair.
Reference: NICE – 2014 – CG188 Gallstone disease; RCOA – 2023 – Hepatobiliary anaesthesia