Chlorhexidine Allergy Alternative — FRCA Final MCQ

Instant feedback + full explanation. One question, done properly.

EasyAnaesthetic Equipment & SafetyChlorhexidine Allergy AlternativeFRCA Final

A 45-year-old man (ASA II) with a history of previous anaphylaxis to chlorhexidine is scheduled for central venous catheter insertion. Which antiseptic should be used as an alternative for skin preparation?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Povidone-iodine

Povidone-iodine is the recommended alternative antiseptic when chlorhexidine is contraindicated (allergy). Chlorhexidine in any concentration must be avoided in patients with documented allergy. While alcoholic chlorhexidine 2% is the gold standard for CVC insertion site preparation (NICE CG139), povidone-iodine 10% in alcohol provides an effective alternative with proven antiseptic efficacy. All chlorhexidine-containing products in the vicinity should be removed (including chlorhexidine-impregnated CVC dressings and catheters).

Reference: NICE – 2017 – CG139 Healthcare-associated infections; Association of Anaesthetists – 2019 – Chlorhexidine allergy