MI Aspirin 300mg Dose — ORE Part 1 MCQ

Instant feedback + full explanation. One question, done properly.

EasyPharmacology & TherapeuticsMI Aspirin 300mg DoseORE Part 1

An adult develops symptoms suggestive of acute myocardial infarction during dental treatment. While awaiting emergency transfer, what single dose of aspirin should be given, provided there is no known aspirin allergy?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — 300 mg

Explanation lettering: B = shown as A · E = shown as B · A = shown as C · C = shown as E

The correct answer is **A: 300 mg**. NICE advises giving a single 300 mg aspirin loading dose as soon as possible for suspected acute coronary syndrome, including suspected MI, unless there is clear evidence of aspirin allergy. This should be given while arranging urgent ambulance transfer, not instead of it. Option B, 75 mg, is associated with low-dose long-term antiplatelet treatment and is insufficient as the acute loading dose. Options C and D are not recommended acute loading doses in UK guidance. Option E is incorrect because aspirin should be given unless contraindicated, particularly by aspirin hypersensitivity; the stem states that there is no known allergy.

Reference: NICE. Recent-onset chest pain of suspected cardiac origin: assessment and diagnosis (CG95), section 1.2.3, Immediate management of a suspected acute coronary syndrome; current page reviewed 27 March 2026. https://www.nice.org.uk/guidance/cg95/chapter/Recommendations