Kelly Syndrome Features — ORE Part 1 MCQ
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Correct answer: C — Combination syndrome (Kelly syndrome)
The correct answer is **A, combination syndrome (Kelly syndrome)**. It is classically associated with a complete maxillary denture opposing retained mandibular anterior teeth. The discriminating findings are anterior maxillary ridge resorption, enlargement of the maxillary tuberosities and papillary hyperplasia of the hard palate; other recognised features may include over-eruption of the mandibular anterior teeth and posterior mandibular ridge resorption. The pattern reflects adverse anterior loading and loss of stable posterior support. Denture stomatitis may cause erythema and sometimes papillary hyperplasia, but does not explain the characteristic ridge and tuberosity changes. Sjögren syndrome causes xerostomia, not this anatomical constellation. Pierre Robin sequence is a congenital craniofacial condition, and Papillon-Lefèvre syndrome is an inherited keratoderma with severe periodontitis.
Reference: Gómez-Polo M et al. Anterior Hyperfunction Syndrome: Literature Review and Conceptual Model. 2024. https://pubmed.ncbi.nlm.nih.gov/39194932/