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Acromegaly Dental Features — ORE Part 1 MCQ

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HardHuman Disease & Dental ManagementAcromegaly Dental FeaturesORE Part 1

Which combination of oral findings is most characteristic of acromegaly in an adult dental patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: CMandibular prognathism, interdental spacing, macroglossia and thickened oral soft tissues

Acromegaly causes gradual skeletal and soft-tissue overgrowth after epiphyseal fusion. Characteristic oral findings include mandibular enlargement with prognathism, widening of the dental arches with interdental spacing, macroglossia and thickened lips/other oral soft tissues. These changes may produce malocclusion and can make prosthetic planning more complex; macroglossia and upper-airway soft-tissue enlargement are also relevant when considering sedation or general anaesthesia. Option A describes the opposite pattern of deficient growth. Option B suggests a developmental enamel/dental-size disorder rather than acquired adult GH excess. Option D again describes reduced rather than excessive skeletal and soft-tissue growth. Option E is not the characteristic oro-dental phenotype and incorrectly limits the presentation to dental disease.

Reference: Kreitschmann-Andermahr I et al. "Oro-dental pathologies in acromegaly." Endocrine, 2018. https://pubmed.ncbi.nlm.nih.gov/29520625/