Glucagon Dose Hypoglycaemia — ORE Part 1 MCQ
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Correct answer: C — 1 mg intramuscularly
Explanation lettering: C = shown as A · A = shown as C · E = shown as D · D = shown as E
The correct dose is 1 mg intramuscularly. This is the consistent, evidence-based standard across all UK NHS formularies, regional protocols, and eMC SmPCs for emergency treatment of unconscious hypoglycaemia in adults. While SmPCs reference a range of 0.5–1 mg, all UK clinical guidance for acute severe hypoglycaemia recommends 1 mg as the standard parenteral dose. Option B (0.5 mg) is the lower end of the SmPC range but is not the recommended standard dose in UK emergency protocols. Options C, D and E are incorrect and exceed or fall well below the evidence-based range. In the dental surgery emergency context, 1 mg is the universally endorsed dose for rapid glucagon administration when an adult patient is unconscious.
Reference: UK NHS Formularies (Birmingham and Surrounds, NHS Scotland, Devon), eMC SmPCs (medicines.org.uk), and NHS regional protocols (Milton Keynes, NTW) all specify 1 mg IM for unconscious adult hypoglycaemia. 2023. https://www.birminghamandsurroundsformulary.nhs.uk/docs/files/BSol%20IMOC%20Management%20of%20hypoglycaemia%20in%20primary%20care%20v1.2%202023.pdf