Nystatin Administration — ORE Part 1 MCQ
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Correct answer: A — Keep it in contact with oral lesions before swallowing and continue for 48 hours after symptoms resolve
Explanation lettering: C = shown as B · D = shown as C · B = shown as D
A is correct. Nystatin acts locally in the mouth, so the suspension should be retained in contact with affected mucosa for as long as possible before swallowing. UK product information also states that treatment should continue for at least 48 hours after symptoms have disappeared, reducing the risk of relapse. B is wrong because immediate swallowing minimises contact with oral lesions. C is wrong because dilution is not recommended and may reduce therapeutic efficacy. D is incomplete: although oral contact is correct, stopping as soon as symptoms resolve is premature. E is also wrong because it omits the required local-contact technique and post-resolution continuation period.
Reference: Vygoris Limited. Nystan Oral Suspension (Ready-Mixed) Summary of Product Characteristics, sections 4.2 and 6.6; revised July 2023, eMC updated 20 June 2024. https://www.medicines.org.uk/emc/product/408/smpc