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Adrenaline Dose Anaphylaxis — ORE Part 1 MCQ

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EasyPharmacology & TherapeuticsAdrenaline Dose AnaphylaxisORE Part 1

What is the correct adult dose of intramuscular adrenaline for the treatment of anaphylaxis in the dental surgery?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A500 micrograms (0.5 mL of 1 mg/mL solution)

Explanation lettering: C = shown as B · D = shown as C · B = shown as D

The correct answer is A: 500 micrograms (0.5 mL of 1 mg/mL solution). This is the standard first-line IM dose for anaphylaxis in adults according to Resuscitation Council UK, the eMC Summary of Product Characteristics, SDCEP, and all major NHS protocols. The IM route is recommended for all non-specialist healthcare providers, including dentists. Option B (300 micrograms) is appropriate for children aged 6–12 years, not adults. Option C (1 mg) is double the recommended dose and risks adverse effects. Options D (150 micrograms) and E (250 micrograms) are subtherapeutic. Further doses may be repeated at 5-minute intervals if symptoms persist.

Reference: Resuscitation Council (UK) and eMC SmPC for Adrenaline Injection BP 1/1000; SDCEP Practice Support Manual (current); NHS Specialist Pharmacy Service, https://www.snprs.scot.nhs.uk/wp-content/uploads/files/anaphylaxis.pdf