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Post-Stroke Depression – Prevalence and Impact — SCE Neurology MCQ

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EasyCerebrovascular DiseasePost-Stroke Depression – Prevalence and ImpactSCE Neurology

A 60-year-old man with a right MCA stroke develops depression at 3 months post-stroke. His PHQ-9 is 17 (moderate-severe). What is the prevalence of post-stroke depression, and why is treatment important?

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Correct answer: B — Post-stroke depression affects approximately 30–33% of stroke survivors and is associated with worse rehabilitation outcomes, higher mortality, increased disability, reduced quality of life, and cognitive impairment — treatment with SSRIs and/or psychological therapy significantly improves outcomes

Post-stroke depression (PSD) is common (~30–33% at any time point after stroke) and is one of the strongest predictors of poor rehabilitation outcome. It is associated with: increased mortality, greater disability, reduced quality of life, cognitive impairment, and increased healthcare utilisation. NICE CG162 recommends screening for depression in all stroke survivors and treating with SSRIs (sertraline/citalopram) and/or psychological therapy. Treatment improves mood, rehabilitation participation, and functional outcomes. A: PSD is common. C: Depression significantly worsens outcomes. D: Both medication and psychology help. E: Many patients require active treatment.

Reference: NICE CG162; NICE CG90 Depression; RCP Stroke Guidelines