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Spasticity Medications – Driving Advice — SCE Neurology MCQ

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EasyMultiple Sclerosis & CNS InflammationSpasticity Medications – Driving AdviceSCE Neurology

A 50-year-old man with MS has bilateral lower limb spasticity and takes baclofen and tizanidine. He asks about driving while on these medications. What advice applies?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: ABoth baclofen and tizanidine can cause drowsiness and impair driving ability — patients should be advised not to drive if affected, and this should be documented; DVLA should be notified about the underlying MS regardless

Both baclofen and tizanidine are centrally acting muscle relaxants that commonly cause drowsiness, dizziness, and cognitive dulling. DVLA and BNF advise that patients should be warned about the potential effects on driving and should not drive if affected. This is separate from (and additive to) the DVLA requirements for MS itself. Documentation of this advice is important medicolegally. A: Both can impair driving. C: Both can cause drowsiness. D: Both can cause drowsiness. E: While spasticity reduction may help function, the sedating effects can impair driving.

Reference: DVLA (2025); BNF – Baclofen, Tizanidine