At the six-hour assessment after first-dose fingolimod, an asymptomatic adult has heart rate 44 bpm, QTc 470 ms and no AV block. Which disposition

Question

At the six-hour assessment after first-dose fingolimod, an asymptomatic adult has heart rate 44 bpm, QTc 470 ms and no AV block. Which disposition follows the SmPC?

Accepted Answer

Continue monitoring at least overnight and until the bradycardia has resolved

Answer

Continue ambulatory ECG monitoring at home and review the trace the next day

Answer

Extend observation for 2 hours and discharge if the heart rate remains stable

Answer

Withhold the next dose and restart later using an alternate-day titration schedule

Answer

Give atropine, then discharge after 2 hours if the rhythm remains sinus

Mirror Therapy – Principle — SCE Neurology MCQ

At the six-hour assessment after first-dose fingolimod, an asymptomatic adult has heart rate 44 bpm, QTc 470 ms and no AV block. Which disposition follows the SmPC?