Intratumoral Haemorrhage – Tumour Types — SCE Neurology MCQ

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ModerateNeuro-oncologyIntratumoral Haemorrhage – Tumour TypesSCE Neurology

A 60-year-old woman with a known right frontal brain tumour develops acute onset left-sided weakness and headache. CT head shows intratumoral haemorrhage. What tumour types are most commonly associated with haemorrhage?

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Correct answer: B — Metastatic melanoma, renal cell carcinoma, choriocarcinoma, thyroid carcinoma, and glioblastoma — these tumour types have a high propensity for intratumoral haemorrhage

Tumour types with the highest propensity for intratumoral haemorrhage include: melanoma metastasis (most haemorrhagic), renal cell carcinoma metastasis, choriocarcinoma metastasis, thyroid carcinoma metastasis, and glioblastoma (among primary brain tumours). The mnemonic 'MR CT' (Melanoma, Renal, Choriocarcinoma, Thyroid) helps remember the most haemorrhagic metastatic tumours. GBM frequently haemorrhages due to neovascularisation with fragile vessels. A: Meningiomas rarely haemorrhage. C: Low-grade astrocytomas rarely bleed. D: Craniopharyngiomas rarely haemorrhage. E: Pituitary microadenomas cause haemorrhage only in apoplexy.

Reference: NICE NG99; Neurosurgical Principles