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EDSS – Scale Interpretation — SCE Neurology MCQ

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EasyMultiple Sclerosis & CNS InflammationEDSS – Scale InterpretationSCE Neurology

A 50-year-old woman with MS develops Lhermitte sign, urinary urgency, and mild bilateral leg weakness during a relapse. She is treated with IV methylprednisolone. Three months later she has residual mild spasticity and urinary urgency but is functionally independent. Her EDSS is 2.5. What does an EDSS of 2.5 indicate?

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Correct answer: E — Minimal disability in two functional systems — the patient is fully ambulatory

The Expanded Disability Status Scale (EDSS) ranges from 0 (normal neurological examination) to 10 (death from MS). EDSS 2.5 indicates minimal disability in two functional systems (FS grade 2 in two systems). The patient is fully ambulatory without aids. Key EDSS landmarks: 4.0 = fully ambulatory for ≥500 m; 6.0 = walks with unilateral aid for ≥100 m; 6.5 = walks with bilateral aids for ≥20 m; 7.0 = wheelchair-bound; 8.0 = bed-bound. A: Wheelchair-dependent is EDSS 7.0+. C: Walking with aid is EDSS 6.0. D: EDSS 10 = death. E: EDSS 0 = no disability.

Reference: NICE NG100 MS; Kurtzke EDSS