CBZ Toxicity — SCE Neurology MCQ

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EasyEpilepsy & Seizure DisordersCBZ ToxicitySCE Neurology

A man on carbamazepine with level 55 µmol/L (therapeutic 20–50) has diplopia, ataxia, nystagmus. Classic toxicity signs?

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Correct answer: C — Diplopia, ataxia, nystagmus, drowsiness — cerebellar/brainstem dysfunction

CBZ toxicity: cerebellar and brainstem signs. Higher levels: cardiac effects, seizures, coma. A: Lithium toxicity features. C: Not acute toxicity. D: Only at very high levels. E: No renal effect.

Reference: BNF; NICE NG217