MS – Exercise Safety and Benefits — SCE Neurology MCQ

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EasyMultiple Sclerosis & CNS InflammationMS – Exercise Safety and BenefitsSCE Neurology

A 40-year-old man with RRMS asks about the role of exercise. He is concerned that exercise will worsen his MS or cause relapses. What does the evidence show?

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Correct answer: E — Exercise is safe and beneficial in MS — it improves fitness, fatigue, mood, and quality of life without increasing relapse rate

Multiple systematic reviews and meta-analyses have shown that regular exercise in MS is safe, does not increase relapse rate, and provides significant benefits including improved aerobic fitness, strength, balance, fatigue, mood, and quality of life. NICE NG100 recommends encouraging physical activity and exercise for people with MS. Exercise programmes should be tailored to the individual's abilities and supervised where possible. Temporary symptom worsening during/after exercise (Uhthoff phenomenon from heat) is not harmful and resolves with cooling. A: Exercise does not worsen MS. C: Exercise has clear benefits. D: Moderate-to-vigorous exercise is safe. E: Exercise is safe at all phases.

Reference: NICE NG100 MS (2022); Motl et al. Cochrane Review MS and Exercise