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RLS – Dopaminergic Augmentation — SCE Neurology MCQ

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HardSleep DisordersRLS – Dopaminergic AugmentationSCE Neurology

A 60-year-old with restless legs syndrome has taken ropinirole for three years. Symptoms now start at 4 pm, spread to the arms and intensify as the dose is increased. Which intervention best addresses the medication-related complication?

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Correct answer: AGradually reduce ropinirole and transition to an alpha-2-delta ligand after iron assessment

This is dopamine-agonist augmentation. Avoid further dose escalation: assess and correct iron deficiency, taper the dopamine agonist and use a non-dopaminergic alternative such as an alpha-2-delta ligand where appropriate.

Reference: NICE CKS, Restless legs syndrome: https://cks.nice.org.uk/topics/restless-legs-syndrome/