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OSA – Weight Loss Benefit — SCE Neurology MCQ

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EasySleep DisordersOSA – Weight Loss BenefitSCE Neurology

A 50-year-old man presents with excessive daytime sleepiness. His partner reports loud snoring and witnessed apnoeas. His BMI is 42. He has an Epworth Sleepiness Scale of 20/24. Overnight polysomnography shows an AHI of 45/hour. He is started on CPAP but asks about additional weight management. What does the evidence show regarding weight loss in OSA?

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Correct answer: A — Weight loss can significantly reduce AHI and may cure OSA in some patients, and should be encouraged alongside CPAP

Weight loss is strongly recommended as an adjunct to CPAP therapy in obese patients with OSA. Studies have shown that significant weight loss (e.g. through bariatric surgery or intensive lifestyle interventions) can substantially reduce AHI, improve symptoms, and in some cases resolve OSA entirely, potentially allowing CPAP cessation. However, CPAP should be continued until repeat sleep studies confirm resolution. A: Weight loss has significant effects. C: Weight loss is beneficial alongside CPAP. D: Weight loss improves OSA. E: CPAP should not be stopped without confirmatory testing.

Reference: NICE NG202 Obstructive Sleep Apnoea (2021)