MS – Bladder Management — SCE Neurology MCQ

Instant feedback + full explanation. One question, done properly.

EasyMultiple Sclerosis & CNS InflammationMS – Bladder ManagementSCE Neurology

A 55-year-old man with MS has bladder symptoms from detrusor overactivity. Oxybutynin caused intolerable dry mouth. What is the next step per NICE NG100?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Mirabegron or an alternative antimuscarinic

If oxybutynin is not tolerated, alternative antimuscarinics (solifenacin, tolterodine) or mirabegron (beta-3 agonist with fewer anticholinergic effects) should be tried. Botulinum toxin is for cases refractory to oral therapy. A: ISC is for incomplete emptying. C: Desmopressin is for nocturia. D: Botulinum toxin is next-line if oral therapy fails. E: Suprapubic catheter is a last resort.

Reference: NICE NG100 MS (2022)