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Steroid-Induced AVN — SCE Neurology MCQ

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ModerateMultiple Sclerosis & CNS InflammationSteroid-Induced AVNSCE Neurology

A 45-year-old woman with MS is being treated with IV methylprednisolone for an acute relapse. She develops bilateral hip pain 3 months later. MRI shows bilateral femoral head AVN. What is the cause?

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Correct answer: B — Corticosteroid-induced avascular necrosis

AVN of the femoral head is a recognised complication of corticosteroid use, even short courses of high-dose IVMP. Risk increases with cumulative exposure. A: OA is degenerative. C: Septic arthritis is monoarticular with fever. D: Stress fractures have different imaging. E: MS does not directly cause bone necrosis.

Reference: BNF – Corticosteroid Side Effects