Lhermitte Sign — SCE Neurology MCQ

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EasyMultiple Sclerosis & CNS InflammationLhermitte SignSCE Neurology

A 28-year-old man has an electric shock sensation down his spine on neck flexion. MRI cervical spine shows T2 hyperintensity at C3. What is this symptom?

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Correct answer: C — Lhermitte sign

Lhermitte sign: electric shock-like sensation on neck flexion indicating cervical dorsal column dysfunction. Most common in MS but also cervical spondylosis, radiation myelopathy, B12 deficiency. A: Uhthoff is heat-related. C: Spurling is for radiculopathy. D: Hoffman is a UMN sign. E: Brown-Séquard is hemisection.

Reference: NICE NG100 MS (2022)