Miller Fisher – Anti-GQ1b — SCE Neurology MCQ

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EasyPeripheral Neuropathy & NeuromuscularMiller Fisher – Anti-GQ1bSCE Neurology

A 30-year-old man presents with ophthalmoplegia, ataxia, and areflexia with normal limb power following an URTI. CSF protein elevated with 1 cell. Which antibody is associated?

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Correct answer: A — Anti-GQ1b

Miller Fisher syndrome: ophthalmoplegia, ataxia, areflexia. Anti-GQ1b IgG positive in >90%. A: Anti-GM1 is for AMAN/MMN. C: Anti-MAG is for paraproteinaemic neuropathy. D: Anti-AChR is for MG. E: Anti-CASPR2 is for Isaac/Morvan syndrome.

Reference: EAN/PNS GBS Guidelines (2023)