Tardive Dyskinesia — SCE Neurology MCQ

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EasyMovement DisordersTardive DyskinesiaSCE Neurology

A 28-year-old woman on metoclopramide for 8 weeks develops involuntary jaw movements, tongue protrusion, and lip smacking. What is the most likely diagnosis?

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Correct answer: B — Tardive dyskinesia

Tardive dyskinesia is caused by chronic dopamine receptor blockade (antipsychotics, metoclopramide). It presents with involuntary repetitive orofacial movements. MHRA advises metoclopramide should not be used >5 days. B: Acute dystonia occurs within hours, not weeks. C: HD is progressive with family history. D: Primary oromandibular dystonia is not drug-related. E: Tics are suppressible.

Reference: MHRA Metoclopramide Safety Alert; BNF