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MS – Cognitive Assessment — SCE Neurology MCQ

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ModerateMultiple Sclerosis & CNS InflammationMS – Cognitive AssessmentSCE Neurology

A 65-year-old woman with MS has progressive cognitive decline affecting processing speed, attention, and executive function. She scores 24/30 on the MoCA. She remains independent in basic ADLs but struggles with complex tasks. What cognitive assessment tool is specifically recommended for monitoring cognitive function in MS?

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Correct answer: CSymbol Digit Modalities Test

The Symbol Digit Modalities Test (SDMT) is the recommended screening and monitoring tool for cognitive function in MS. It specifically tests processing speed, which is the most commonly affected cognitive domain in MS. It is sensitive to change, quick to administer (90 seconds), and has good test-retest reliability. NICE NG100 recommends regular cognitive assessment in MS. A: MMSE is insensitive to MS-related cognitive deficits. B: MoCA is useful but not MS-specific. D: ACE-III is comprehensive but not validated specifically for MS monitoring. E: Clock Drawing Test tests visuospatial function primarily.

Reference: NICE NG100 MS (2022); ABN MS Guidelines (2022)