skip to main content

MS Acute Relapse — SCE Neurology MCQ

Instant feedback + full explanation. One question, done properly.

EasyMultiple Sclerosis & CNS InflammationMS Acute RelapseSCE Neurology

A 30-year-old woman presents with an acute MS relapse causing severe right optic neuritis with visual acuity of 6/60. What is the first-line treatment for this acute relapse?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Intravenous methylprednisolone 1 g daily for 3–5 days

NICE NG100 recommends IV methylprednisolone (typically 1 g daily for 3–5 days) as first-line treatment for acute MS relapses that cause significant functional impairment. A: Low-dose oral steroids are not adequate for acute relapses. C: Plasma exchange is considered if steroids fail. D: IVIG is not standard treatment for MS relapses. E: Interferon beta is a preventive DMT, not a relapse treatment.

Reference: NICE NG100 MS (2022)