PLD Compromising PD Switch HD — ESENeph MCQ

Correct answer: E — Continue the effective initial antibiotics for 2 weeks

The best answer is “Continue the effective initial antibiotics for 2 weeks”. ISPD recommends a 2-week course for culture-negative peritonitis that resolves promptly. Failure to improve triggers repeat cell count, culture-method review and investigation for resistant or unusual organisms. “Stop antibiotics as soon as the culture is reported negative” is less appropriate because culture negativity does not exclude bacterial peritonitis “Remove the catheter immediately despite prompt clinical response” is less appropriate because automatic removal is not indicated for a responding first culture-negative episode “Continue treatment for 6 weeks” is less appropriate because this exceeds the recommended course without a refractory or unusual organism “Use antifungal monotherapy because bacteria were not cultured” is less appropriate because culture-negative bacterial peritonitis is more likely when the response to empiric antibacterial therapy is prompt

Reference: ISPD 2022 peritonitis guideline: https://pubmed.ncbi.nlm.nih.gov/35264029/