At 18 weeks of pregnancy, a woman with known CKD has serum creatinine 104 µmol/L. The laboratory reports eGFR 58 mL/min/1.73m² using CKD-EPI. How

Question

At 18 weeks of pregnancy, a woman with known CKD has serum creatinine 104 µmol/L. The laboratory reports eGFR 58 mL/min/1.73m² using CKD-EPI. How should her renal trajectory be assessed?

Accepted Answer

Use serial serum creatinine; eGFR equations are invalid in pregnancy

Answer

Use cystatin-C eGFR as the validated pregnancy reference standard

Answer

Use urea clearance alone because serum creatinine falls unpredictably in every pregnancy

Answer

Replace CKD-EPI with Cockcroft–Gault using pre-pregnancy body weight

Answer

Use the reported CKD-EPI eGFR after multiplying it by gestational age

MMF Washout Pre-Conception LN — ESENeph MCQ

At 18 weeks of pregnancy, a woman with known CKD has serum creatinine 104 µmol/L. The laboratory reports eGFR 58 mL/min/1.73m² using CKD-EPI. How should her renal trajectory be assessed?