Cancer-Free Interval Transplant Listing Colorectal — ESENeph MCQ

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ModerateTransplantationCancer-Free Interval Transplant Listing ColorectalESENeph

A 74-year-old man with CKD G4 (eGFR 22 mL/min/1.73m2) is referred for transplant assessment. He had a Dukes B colorectal carcinoma resected 3 years ago with clear margins and no adjuvant therapy. Follow-up colonoscopies have been normal. What is the recommended cancer-free interval before transplant listing?

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Correct answer: B — At least 2 years — he can be listed now

Explanation lettering: B = shown as A · E = shown as B · A = shown as D · D = shown as E

Dukes B colorectal carcinoma is localized/node-negative disease treated with curative resection. Current kidney-transplant candidate guidance recommends a minimum cancer-free interval of at least 2 years for colorectal cancer Dukes A/B before transplantation/list activation. This patient is 3 years post-resection, has clear margins, required no adjuvant therapy, and has normal surveillance colonoscopies, so he has exceeded the required interval and can be listed now. Colorectal carcinoma is not a permanent contraindication, and 5–10 years is reserved for higher-risk or more advanced malignancy categories.

Reference: KDIGO Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation, 2020, Table 14: recommended waiting time for colorectal cancer Dukes A/B is at least 2 years. https://kdigo.org/wp-content/uploads/2026/04/KDIGO-2020-Transplant-Candidate-Guideline.pdf