Heparin Timing Dental Procedure Dialysis — ESENeph MCQ
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Correct answer: C — Heparinise normally on Monday — no adjustment needed as extraction is 2 days away
With dental extraction scheduled for Wednesday and dialysis on Monday, standard heparinisation on Monday is appropriate. Standard unfractionated heparin has a half-life of approximately 1-2 hours and is fully cleared within 4-6 hours. By Wednesday (>48 hours later), there is no residual anticoagulant effect. Heparin-free dialysis or citrate anticoagulation would only be necessary if the procedure were planned within 4-12 hours of the dialysis session (e.g., same day or next morning). For procedures within 12 hours of dialysis, heparin-free dialysis or regional citrate should be used. This question tests understanding of heparin pharmacokinetics in dialysis patients.
Reference: UKKA 2019 – Haemodialysis Guidelines; BSH 2011 – Perioperative Anticoagulation Management