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SGLT2i HFpEF Benefit CKD — ESENeph MCQ

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HardChronic Kidney DiseaseSGLT2i HFpEF Benefit CKDESENeph

A haemodialysis patient with secondary hyperparathyroidism is changing from oral cinacalcet to intravenous etelcalcetide. Corrected calcium is normal. When may Parsabiv be initiated?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — After a 7-day cinacalcet washout and once corrected calcium is normal

Explanation lettering: B = shown as A · A = shown as B · D = shown as C · E = shown as D · C = shown as E

D is correct. Etelcalcetide should not start until seven days after the last cinacalcet dose and until corrected calcium is at or above the lower limit of normal. Overlap would compound calcimimetic hypocalcaemia. PTH helps titrate later treatment, but it does not replace the calcium and washout conditions for switching.

Reference: Parsabiv solution for injection SmPC: https://www.medicines.org.uk/emc/product/4417/smpc