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Sodium Restriction Strongest Lifestyle CKD — ESENeph MCQ

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EasyChronic Kidney DiseaseSodium Restriction Strongest Lifestyle CKDESENeph

A 48-year-old man with type 2 diabetes and CKD G3bA3 is on the full four-pillar regimen. His nephrologist mentions that KDIGO 2024 also recommends lifestyle interventions. What specific lifestyle measure has the strongest evidence for slowing CKD progression?

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Correct answer: C — Dietary sodium restriction (<2 g/day)

KDIGO 2024 includes lifestyle management as a foundational component of CKD care. Among dietary interventions, sodium restriction (<2 g/day, ~5 g salt/day) has the strongest and most consistent evidence for augmenting pharmacological renoprotection. Sodium restriction: enhances RASi antiproteinuric effect (high sodium intake blunts ACEi/ARB efficacy by 40-50%), reduces BP, decreases fluid retention, and may independently slow CKD progression. In practice, most CKD patients consume 3-5 g sodium/day. Dietetic support is critical. Other important lifestyle measures include regular exercise (≥150 min/week), weight management, and smoking cessation.

Reference: https://guidelines.ukkidney.org