Captopril Renogram Interpretation RAS — ESENeph MCQ
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Correct answer: A — Roxadustat for eligible non-dialysis CKD anaemia
The best answer is “Roxadustat for eligible non-dialysis CKD anaemia”. NICE recommends roxadustat as an option for symptomatic anaemia in adults with CKD G3-G5, no iron deficiency and no dialysis at initiation. Choice against ESA considers route, risks, preferences and cost. “Roxadustat is restricted to iron-deficient patients before iron replacement” is less appropriate because the appraisal population has no iron deficiency “Roxadustat is reserved for initiation after maintenance dialysis begins” is less appropriate because TA807 covers people not on dialysis at treatment start “Roxadustat replaces investigation for other causes of anaemia” is less appropriate because other causes and iron deficiency must still be assessed “Roxadustat must be combined with full-dose ESA” is less appropriate because it is an alternative erythropoietic strategy rather than routine combination therapy
Reference: NICE TA807: roxadustat for symptomatic CKD anaemia: https://www.nice.org.uk/guidance/ta807/chapter/1-Recommendations