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Group II Gadolinium Safe CKD — ESENeph MCQ

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EasyChronic Kidney DiseaseGroup II Gadolinium Safe CKDESENeph

A 55-year-old man with CKD G3b is considered for MRI with Gadobutrol (Group II macrocyclic). His eGFR is 35. Is this safe?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AYes – Group II macrocyclic agents have negligible NSF risk even in advanced CKD and can be used at eGFR 35 with clinical indication

Group II macrocyclic agents have extremely high stability with no unconfounded NSF cases reported. ESUR 2018 and ACR 2022 classify them as lowest risk.

Reference: ESUR 2018; ACR 2022 – Contrast Manual