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Aminoglycoside Ototoxicity HD — ESENeph MCQ

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ModerateHaemodialysisAminoglycoside Ototoxicity HDESENeph

A 55-year-old woman on HD develops hearing loss after 3 years of intermittent Gentamicin for catheter infections. What is the likely cause?

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Correct answer: CAminoglycoside cumulative ototoxicity – irreversible cochlear and vestibular hair cell destruction; risk increases with total dose, CKD, and concurrent ototoxins

Aminoglycoside ototoxicity is cumulative and irreversible. In dialysis patients on repeated Gentamicin courses, audiometry monitoring should be considered.

Reference: BNF 2024 – Gentamicin; NICE Aminoglycoside Safety