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Uraemic Female Sexual Dysfunction — ESENeph MCQ

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HardHaemodialysisUraemic Female Sexual DysfunctionESENeph

Belatacept is considered for immunosuppression after kidney transplantation, but the recipient’s EBV serostatus cannot be confirmed from available records. What is the correct decision?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Do not give belatacept because EBV-seronegative or unknown status is contraindicated

Explanation lettering: D = shown as A · C = shown as B · A = shown as C · E = shown as D · B = shown as E

A is correct. NULOJIX is contraindicated when the recipient is EBV seronegative or the serostatus is unknown because belatacept-associated post-transplant lymphoproliferative disorder is more frequent in EBV-seronegative recipients and often involves the CNS. Recipient serology must therefore be ascertained before treatment; donor status or antiviral prophylaxis does not substitute for it.

Reference: NULOJIX 250 mg powder for concentrate for solution for infusion SmPC: https://www.medicines.org.uk/emc/product/4685/smpc