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Living Donor Evaluation Framework KDIGO — ESENeph MCQ

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EasyTransplantationLiving Donor Evaluation Framework KDIGOESENeph

A 40-year-old man is being evaluated as a potential living kidney donor. His eGFR is 95, BP is 118/72, BMI is 25, uACR is normal, and he has no medical conditions. According to KDIGO 2017 living donor guideline, what is the framework for donor evaluation?

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Correct answer: A — Comprehensive evaluation of medical suitability (including projected lifetime ESKD risk from donation), psychosocial assessment, informed consent about short-term surgical risks and long-term renal/cardiovascular consequences, and ensuring voluntary non-coerced decision-making

KDIGO 2017 living donor guideline established a comprehensive risk-based framework: (1) Medical evaluation: projected lifetime ESKD risk (integrating age, eGFR, BMI, BP, family history, ethnicity, sex – the acceptable threshold is typically <1% post-donation ESKD risk); (2) Surgical risk: perioperative mortality ~0.03%, major complications ~2-4%; (3) Long-term outcomes: slight increase in ESKD risk (from ~0.03% to ~0.09% lifetime) and mild BP increase; (4) Psychosocial: voluntary decision, no coercion, understanding of implications; (5) Informed consent: documented discussion of risks, alternatives, and the right to withdraw at any stage.

Reference: KDIGO 2017 – Living Kidney Donor Evaluation Guideline