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Respiratory Alkalosis Liver Disease — ESENeph MCQ

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HardAcid-BaseRespiratory Alkalosis Liver DiseaseESENeph

A previously well adult has a first eGFR result of 54 mL/min/1.73m² with no earlier creatinine available and no acute illness. What is the next step needed to exclude an acute deterioration?

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Correct answer: A — Repeat eGFR within 2 weeks

The best answer is “Repeat eGFR within 2 weeks”. NICE advises repeating a new reduced GFR within 2 weeks to exclude an acute deterioration before chronicity is assumed. A three-month interval is relevant to confirming CKD persistence, but it is too late for the immediate safety check. Biopsy and dialysis planning are not justified by one mildly reduced result.

Reference: NICE NG203 chronic kidney disease recommendations: https://www.nice.org.uk/guidance/ng203/chapter/Recommendations