skip to main content

MGRS Monoclonal Gammopathy Renal — ESENeph MCQ

Instant feedback + full explanation. One question, done properly.

HardGlomerulonephritisMGRS Monoclonal Gammopathy RenalESENeph

A kidney candidate has cPRA 98% after pregnancies and a failed graft. Which UK allocation principle improves access to a rare compatible deceased-donor kidney?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: AUse sensitisation and matchability within the national kidney offering scheme

The best answer is “Use sensitisation and matchability within the national kidney offering scheme”. NHSBT incorporates antibody-defined compatibility, sensitisation and matchability so that uncommon acceptable offers can be prioritized safely for highly sensitised candidates. “Register through the national offering scheme at the transplant centre” is less appropriate because allocation is national and duplicate listing is not the mechanism “Record unacceptable antigens while assessing sensitisation and matchability” is less appropriate because immunological safety remains essential “Use mismatch priority according to the national allocation algorithm” is less appropriate because the algorithm integrates multiple allocation factors rather than one blanket rule “Consider paired exchange when a willing incompatible living donor exists” is less appropriate because paired exchange requires a donor-recipient pair and is not the deceased-donor mechanism

Reference: NHS Blood and Transplant kidney offering scheme: https://www.odt.nhs.uk/transplantation/tools-policies-and-guidance/policies-and-guidance/