Volume-Dependent Hypertension HD — ESENeph MCQ
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Correct answer: E — Keep patiromer at least 3 hours before or after levothyroxine
Explanation lettering: B = shown as A · D = shown as B · A = shown as C · C = shown as D
E is correct. Patiromer can bind some oral medicines in the gastrointestinal tract; reduced levothyroxine bioavailability was avoided when dosing was separated by three hours. The SmPC therefore uses a three-hour precaution for oral medicines unless interaction data support no separation. This is a binding interaction, not a meal-dependent metabolic effect.
Reference: Veltassa 16.8 g powder for oral suspension SmPC: https://www.medicines.org.uk/emc/product/10416/smpc