A 45-year-old woman with CKD G4 (eGFR 22 mL/min/1.73m2) has a haemoglobin of 82 g/L and is being started on an ESA. She is a potential transplant

Question

A 45-year-old woman with CKD G4 (eGFR 22 mL/min/1.73m2) has a haemoglobin of 82 g/L and is being started on an ESA. She is a potential transplant candidate. What is the target haemoglobin range and why is it important not to exceed the upper limit?

Accepted Answer

Target 100-115 g/L; exceeding 130 g/L increases cardiovascular events, stroke, and vascular access thrombosis

Answer

No target exists – titrate to symptoms

Answer

Target 120-140 g/L as in general population

Answer

Target 130-150 g/L for optimal quality of life

Answer

Target 80-90 g/L to avoid transfusion only

ESA Target Ceiling Rationale — ESENeph MCQ

A 45-year-old woman with CKD G4 (eGFR 22 mL/min/1.73m2) has a haemoglobin of 82 g/L and is being started on an ESA. She is a potential transplant candidate. What is the target haemoglobin range and why is it important not to exceed the upper limit?