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Living Donor Assessment Diabetes Risk — ESENeph MCQ

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ModerateTransplantationLiving Donor Assessment Diabetes RiskESENeph

A 48-year-old man is being assessed for kidney donation. His eGFR is 95 mL/min/1.73m2, BP is 122/78 mmHg, BMI is 26, and he has no proteinuria. He has a family history of diabetes (father, diagnosed age 60). According to KDIGO 2017 living donor guideline, is he an acceptable donor?

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Correct answer: E — He can be considered – family history of diabetes is a risk factor requiring careful assessment but is not an absolute contraindication if current glucose metabolism is normal

KDIGO 2017 living donor guideline takes a risk-based approach. Family history of diabetes is a risk factor for future donor kidney disease but is not an absolute contraindication. If his current glucose metabolism is normal (fasting glucose, HbA1c, oral glucose tolerance test), he can be considered. The donation decision integrates multiple risk factors (age, BMI, BP, family history, ethnicity) into an overall projected post-donation ESKD risk. Informed consent about his long-term risk is essential.

Reference: KDIGO 2017 – Living Kidney Donor Evaluation Guideline