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Malarial AKI — ESENeph MCQ

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HardAcute Kidney InjuryMalarial AKIESENeph

A patient prescribed Kinpeygo for IgA nephropathy cannot comfortably swallow the modified-release capsules and asks to mix their contents into yoghurt. What is the correct advice?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DDo not open, crush or chew the capsules; they must be swallowed whole with water

Explanation lettering: E = shown as A · C = shown as B · B = shown as C · A = shown as D · D = shown as E

A is correct. Kinpeygo modified-release capsules must be swallowed whole with water and must not be opened, crushed or chewed because doing so can alter the release profile. This instruction is formulation-specific. Administration methods used for some enteric granules or ordinary budesonide preparations cannot be assumed to apply.

Reference: Kinpeygo 4 mg modified-release hard capsules SmPC: https://www.medicines.org.uk/emc/product/15393/smpc