Exercise in CKD — ESENeph MCQ

Instant feedback + full explanation. One question, done properly.

HardChronic Kidney DiseaseExercise in CKDESENeph

A kidney transplant recipient has completed the immediate postoperative period without contraindication to antimicrobial prophylaxis. Which regimen reduces Pneumocystis jirovecii pneumonia risk during the first 6 months?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Trimethoprim-sulfamethoxazole

The best answer is “Trimethoprim-sulfamethoxazole”. KDIGO recommends trimethoprim-sulfamethoxazole prophylaxis for all kidney transplant recipients for at least 3 to 6 months after transplantation. Valganciclovir addresses cytomegalovirus risk, fluconazole and amphotericin are antifungals for other indications, and aciclovir does not provide Pneumocystis prophylaxis. The prophylactic choice therefore follows organism coverage rather than broad antimicrobial activity.

Reference: KDIGO kidney transplant recipient guideline: https://kdigo.org/wp-content/uploads/2022/09/KDIGO-2009-Transplant-Recipient-Guideline-English.pdf