skip to main content

SGLT2i Low Albuminuria CKD — ESENeph MCQ

Instant feedback + full explanation. One question, done properly.

ModerateChronic Kidney DiseaseSGLT2i Low Albuminuria CKDESENeph

A 58-year-old woman with CKD G3bA2 (eGFR 42, uACR 12 mg/mmol) and no diabetes has BP 134/82 mmHg on Ramipril 10 mg. She is not on an SGLT2i. According to KDIGO 2024, what is the recommendation regarding SGLT2i in her case?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — SGLT2i is suggested (2B) as she has eGFR 20-45 and ACR <200 mg/g (<20 mg/mmol)

KDIGO 2024 suggests (2B) treating adults with eGFR 20-45 mL/min/1.73m2 and uACR <200 mg/g (<20 mg/mmol) with an SGLT2i. This is a weaker recommendation than the 1A for higher albuminuria or diabetes, but still supports use. The EMPA-KIDNEY trial included patients with eGFR 20-45 regardless of albuminuria level and showed benefit.

Reference: KDIGO 2024 – CKD Guideline