skip to main content

Uraemic Neuropathy — ESENeph MCQ

Instant feedback + full explanation. One question, done properly.

ModerateChronic Kidney DiseaseUraemic NeuropathyESENeph

A 55-year-old man with CKD G4 (eGFR 22 mL/min/1.73m2) develops symptomatic peripheral neuropathy with painful paraesthesiae and weakness. Nerve conduction studies confirm uraemic polyneuropathy. What does this symptom indicate?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — An indication to consider starting renal replacement therapy

Uraemic neuropathy is a late manifestation of CKD (usually CKD G5) and is an important indication for initiating dialysis. NICE NG107 includes symptomatic uraemia (including neuropathy) as an indication for dialysis initiation. While other causes of neuropathy (diabetes, B12 deficiency) should be excluded, confirmed uraemic neuropathy reflects significant uraemic toxin accumulation and should prompt timely RRT planning.

Reference: NICE NG107 2018 – RRT; KDIGO 2024 – CKD