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Malignant Hypertension TMA — ESENeph MCQ

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HardHypertensionMalignant Hypertension TMAESENeph

An adult with persistent hyperkalaemia starts patiromer 8.4 g once daily. Potassium remains above target on day 5 without an emergency indication. Which titration plan follows the UK SmPC?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — At 1 week, increase by 8.4 g daily if potassium remains high

Explanation lettering: C = shown as A · E = shown as B · B = shown as C · A = shown as D · D = shown as E

D is correct. Adult patiromer starts at 8.4 g once daily and is increased or decreased by 8.4 g at intervals of one week or longer according to potassium, to a maximum of 25.2 g daily. Day-5 escalation is premature. The weekly titration interval reflects use for sustained potassium control rather than minute-to-minute emergency correction.

Reference: Veltassa 16.8 g powder for oral suspension SmPC: https://www.medicines.org.uk/emc/product/10416/smpc